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Why does the Shimadzu column oven show a leak when there isn't one?
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Standard performance features, such as excellent baseline stability, ultra-low carryover performance, and excellent reproducibility of sample injection, ensure stable and validated results in any analysis based on national Pharmacopeia of each country. Systems with a PDA detector are ideal for the analysis of synthetic pigments. Qualitative analysis with a UV spectrum and sensitive and simultaneous quantitation by wavelength switching are available.
By adding an optional tungsten lamp, synthetic pigments and other substances measured in the long-wavelength region can be detected with high sensitivity.
Adding the RIDA differential refractive index detector enables the detection of low light-absorbing compounds such as sugar. Furthermore, adding the ELSD-LT II evaporative light scattering detector enables detection of low light absorbing components with a gradient elution method. A remarkably wide range of applications is possible, including simultaneous analysis of multiple components. Analyses of environmentally hazardous substances require high-sensitivity simultaneous detection.
Connecting a worldclass sensitive fluorescence detector, RFAxs, to a system equipped with a UV detector increases detection selectivity and sensitivity, and ensures reliable detection and identification of trace-level of environmental contaminants. For trace amounts of light-absorbing additives in samples, a UV or PDA detector can be used complementarily. Gel permeation chromatography GPC for the analysis of hydrophobic polymers has traditionally been conducted using a differential refractive index detector.
However, when UV-absorbing trace-level additives are present along with the principal synthetic polymer component, these are sometimes analyzed using a UV detector or photodiode array detector PDA for highsensitivity detection. However, a combination of a differential refractive index detector and UV detector makes it possible to conduct simultaneous analysis of the principle component along with any trace-level additives, and further, permits calculation of the molecular weight distribution of the polymer, confirmation of the UV spectra of minor components, and quantitation based on the calibration curve and qualitative analysis results.
The Prominence-i Plus integrated high-performance liquid chromatograph supports connection with the RIDA differential refractive index detector. In addition, as the column oven can house up to three 30 cm columns used for GPC analysis, applications that require a long column are also supported.
Various types of additives, including plasticizers, antioxidants, lubricants, vulcanization accelerators and flame retardants, are generally added to polymers. As shown in Fig. The additive peak, which was barely detected by the differential refractive index detector, was detected with high sensitivity by the PDA detector by optimizing the detection wavelength, thereby permitting quantitation.
Also, as shown in Fig. The new i-Series Plus integrated high-performance liquid chromatograph can be connected to the RIDA differential refractive index detector. For the analytical column, we used the Shim-pack SCRN, a specialized sugar-analysis column that supports both the gel filtration and ligand exchange modes.HPLC has, without a doubt, grown to be the most popular and versatile of all analytical techniques in laboratories today. HPLC can be used for applications in such diverse industries as food and beverages, forensics, pharmaceuticals, drug discovery, environmental, and petrochemical.
With a wide range of systems and components, including data systems, and outstanding reputation for long life, precision, and practically maintenance-free operation, Shimadzu has the resources to meet user requirements in nearly every market and application.
Learn more about our full lineup of HPLC instruments from our analytical web site that can be found here. We are working to add many of our pumps since not all parts are listed at this time. Exploded diagrams are available for select instruments. Autosampler Accessories. We are working to add many of our autosamplers since not all parts are listed at this time.
This realization leads us to now, a time in which AI capabilities have been incorporated to allow devices to detect and resolve issues automatically. In addition, lab management has been integrated using the Internet of Things IoT and device networking, making it simple to review the status of instruments and optimize resource allocation. Automated support functions utilizing digital technology, such as M2M, IoT, and Artificial Intelligence AIthat enable higher productivity and maximum reliability.
Allows a system to monitor and diagnose itself, handle any issues during data acquisition without user input, and automatically behave as if it were operated by an expert. Learn more. This product is certified as Shimadzu's Eco-Products Plus. This page may contain references to products that are not available in your country.
Please contact us to check the availability of these products in your country. More Information Accept Cookies. Overview Features Applications Option System configuration. Intelligence Automated support functions utilizing digital technology, such as M2M, IoT, and Artificial Intelligence AIthat enable higher productivity and maximum reliability.
Particularly for food applications, the combination with the LCMS single quadrupole mass spectrometer provides excellent qualitative capacities, enabling accurate, high-quality quantitative and qualitative analysis. LC-MS is capable of separation by mass and the identification of components from MS spectral information. As a result, LC-MS is used widely in the field of food analysis. This includes the analysis of a wide range of analytes, from effective to toxic components.
In addition to the uncompromised efficiency and quality of analysis, operators benefit from intuitive operation of the color touch panel, remote monitoring and control by smartphone or tablet PC as well as advanced startup and shutdown functions.
These features make the i- Series family an intelligent instrument which fits both large labs requiring high throughput operation as well as small labs with limited bench space. The i -Series increases productivity, e. The i -Series concept combines innovation, intuition and intelligence for applications in food, environmental, chemical and pharmaceutical industries.
The analyzers are de-signed to meet the needs of any analytical environment with high speed, outstanding performance, maintainability and economics. This is at least three hours faster than existing models and competitor products. Changing or adding samples during a run has never been easier, and different combinations of containers can be used.
Useful options such as a column switching valve, mobile phase selection valves and a choice of detectors make it easier to run a large number of assays continuously while enabling multiple operators to share one system without compromising productivity. The color touch panel supports control of the analysis, monitoring instrument status, usage of the system and consumables.
It assists with maintenance and displays a chromatogram. The i -Series is also compatible with mobile devices for remote monitoring and control. In this way, anyone can run Prominence -i or Nexera- i anytime and anywhere. The maximally automated i-Series comprises auto-startup, auto-SST system suitability testquick-batch function, auto-shutdown and auto-validation for system qualification. Solvent and sample consumption can also be reduced to one-fifth of the usual amount without sacrificing data quality.
The i -Series analyzers are designed to meet the needs of any analytical environment with high speed, outstanding performance, maintainability and economics. Figure 1: The new Prominence- i LC LT is a detectorless model giving users the flexibility of adding any detector of choice, e. More: www. Product features and advantages The i -Series concept combines innovation, intuition and intelligence for applications in food, environmental, chemical and pharmaceutical industries.
Intuitive operation The color touch panel supports control of the analysis, monitoring instrument status, usage of the system and consumables. Intelligence The maximally automated i-Series comprises auto-startup, auto-SST system suitability testquick-batch function, auto-shutdown and auto-validation for system qualification. Top of This Page.Rx Only. Product s not available in all countries.
All other products are For Research Use Only. Not for use in Diagnostic Procedures.
Discover how, together, we can break new ground in scientific discovery and diagnostic accuracy. Our extensive portfolio of powerful mass spectrometers enables you conduct quantitative and qualitative analysis across a range of routine and complex analytical workflows.
View All. View All Mass Spectrometers. Meticulously designed, developed and optimized by industry leading scientists, SCIEX Integrated Solutions enable you to advance your current analyses, whether you are a mass spec expert or a complete novice.
View All Integrated Solutions. CESI Plus. PA Plus. CHT Biologics Analyzer. View All Capillary Electrophoresis. Advance your research with front-end instruments designed to help you realize the full power of your mass spectrometer. Differential mobility spectrometry DMS and ion mobility spectrometry are analytical techniques used to separate ions based on their gas phase mobility.
Multiple types of ion mobility devices exist, such as drift tubes, traveling wave, and high-field asymmetric waveform devices. Learn how you can separate yourself with Differential Ion Mobility. View All Ion Sources. Illicit Drugs. Illegal Dyes.
i-Series Plus Integrated HPLC Systems
Industrial Chemicals Bisphenol. Industrial Chemicals Ethanolamines. Pesticides Herbicides. Pesticides Polar. Peptide and Protein Bioanalysis. Routine Biologics Characterization. Blood Screening. Drugs of Abuse. Urine Screening. Software Feature Request Portal. View All Software.
With a comprehensive library at your fingertips, you can easily create methods and process targeted and non-targeted screening data on your complex samples, faster and easier than ever before.
The HPLC system perfect for checking synthetic compounds, quantitative testing with standard operative procedure, etc. This system can offer wide range of industry such as pharmaceuticals, chemicals, foods and environments. This system can be operated as a singleuse system or a shared system.
Its small footprint facilitates the management and relocation of systems. Realization of Advanced Laboratory. Achieving Easier Operation Uniform graphical user interfaces between system and workstation allow intuitive operations regardless of experience level and increase the operation availability of the i-Series.
The browser functions in LabSolutions bring rapid processing of large amount of data, realtime statistical calculation and easy confirmation of anomalous values, enabling more efficient data processing. Combined with the LabSolutions automated functions, it reliably completes analyses under specified procedures. In addition, the E-mail notification feature allows you to focus on other work, without worrying about analysis end time.
A direct access mechanism on sample racks allows the user to place the sample on racks that are not involved in sample injection even during analysis.
Furthermore, racks can be shared by multiple analysts, without interrupting the analysis of samples placed by others. Overall, this function enhances work efficiency. System status and chromatograms can be viewed remotely from smart devices and home computers. Situations can be checked without needing to visit the laboratory.
Greater Efficiency, Greater Ease of Use. Using mannitol analysis as an example In addition to the temperature control function in flow cells, the i-Series Plus employs new temperature control technology for This system allows the direct injection of Due to Shimadzu's proprietary flow channel design, carryover effects from residual samples are reduced to nearly zero. Learn More. Although it is an integrated LC system, the i-Series Plus supports a wide range of applications according to your choice of detectors.
Gel permeation chromatography GPC for the analysis of hydrophobic polymers has traditionally been conducted using a differential refractive index detector. Analysis of Sugars in Juice. The new i-Series Plus integrated high-performance liquid chromatograph can be connected to the RIDA differential refractive index detector. Applications Utilizing i-Series Plus. This page may contain references to products that are not available in your country. Please contact us to check the availability of these products in your country.
More Information Accept Cookies. Maximum Reliability and Stability. Realization of Advanced Laboratory From setting vial to starting analysis, all the procedures are performed via the equipment. The operations in the laboratory are minimized and free of errors. The system status can be supervised even from outside the laboratory.
More efficient use of laboratory space. Pharmaceuticals Foods and Beverages Environmental Chemical.